Off-target variants are the variations that fall out of target regions defined by the manifest file of the sequencing kit. The genes covered by a kit determine the kit’s gene set. Hence, off-target variants can be classified in two. Read More ⇒
With the advancements in high-throughput next generation sequencing (NGS), sequencing has become more affordable and faster. The applicability of NGS at gene panel, exome and genome levels makes it a very versatile and robust option in Read More ⇒
genomize-Seq is a next generation sequencing (NGS) data analysis, management and sharing platform. In this blog letter, we will explain the parameters genomize-Seq employs for variant confidence classification.
genomize-Seq uses a three-level confidence classification scheme, with the classes High, Low and Failed. A parameter optimization is necessary to classify the real variants into high confidence class. No matter Read More ⇒